PowerFuge® P12: A Stainless Steel System for Scaling Processing
Translate optimized workflows from smaller PowerFuge models into mid-scale processing with the automated PowerFuge P12. Combine CIP/SIP capabilities and simple maintenance with the power of 20,000xg for reliable liquid-solid separation.
| Minimum Working Volume 9 L | Flow Rate 4 L/min | G-force Up to 20,000 xg |
Benefits of CARR Biosystems PowerFuge P12
Versatility
Transition from development to manufacturing, handling applications like E. coli harvest, lysate removal, P. pastoris clarification, specialty chemicals, and solvent separations.
Performance
Handle even the most challenging separations with the ability to process bacteria, fungi, proteins, and submicron particles with 20,000 xg separation force.
Durability
Reduce downtime and maintenance costs with robust construction, high-quality materials, comprehensive maintenance, and CIP/SIP capabilities, ensuring fewer parts to replace and longer operational life.
Safety
Maintain controlled process conditions and safely handle hazardous materials and solvents with the PowerFuge P12's closed system design, preventing product waste and minimizing health risks.
The PowerFuge P12 is a high-performance centrifuge for scaling up processing. Its titanium-alloy tubular bowl enables low-shear liquid-solid separation of bacterial, fungal, protein, and submicron particles. The PowerFuge P12 maximizes product yield, handling high-density feeds without dilution while also automating solids removal for improved efficiency.
- Complete liquid/solid separations
- Full Clean-In-Place/Sterilize-In-Place (CIP/SIP)
- Fully automated processes, including solids removal
- Integrated cooling jacket & spindle cooling unit
- Regulatory documentation available
- Closed processing system
| Bowl Volume | 9 L |
| Max Flow Rate | 4 L/min |
| Rotational Force | Up to 20,000 xg |
| Max Concentrate Density | <1.5 g/ml |
| Weight | 1,225-2,025 kg (2,700-4,465 lbs) |
| Maximum Case Pressure | 1 bar (non-SIP), 2 bar (SIP, ASME/PED) 6.9 bar (100 psi) cooling jacket |
| Programmable Logic Controllers (PLC) | Allen-Bradley® or Siemens® |
| Feed | Feedcone acceleration |
| Electrical Requirements | 400V/50Hz or 480V/60Hz (configuration dependent) Spindle cooling unit: 230V/50Hz |
| Pneumatic | Clean, dry air supply 6 bar (90 psi) |
Process Wetted Parts Construction
- 316 and 316L stainless steel
- 17-4PH stainless steel
- Nitronic 60 stainless steel
- High-strength titanium alloy
- Teflon, silicone, ethylene propylene diene monomer (EPDM) O-rings and gaskets
- Stainless steel finish electropolished to 25 Ra
- Titanium alloy bowl tumbled finished to 25 Ra
- Swinglock rollers of polyether ether ketone (PEEK) thermoplastic
The PowerFuge is a continuous flow centrifuge that introduces the feed through a stationary pipe and accelerates it to full rotational speed before entering the titanium-alloy tubular bowl. Centrifugal forces separate solids from liquids, compressing solids against the bowl wall while the supernatant flows into a collection chamber. Compressed solids are periodically removed with a fully automated scraping cycle.
The PowerFuge P12 features:
- Service hoist
- Fully automated, intuitive software accessible through Allen-Bradley HMI touchscreen
- Siemens HMI touchscreen available
- Optional hazardous duty (Class 1, Div 1, Group C and D) and CE configurations available
- Designs available for ASME and PED rated boundary, hazardous locations, and aseptic operations
- Closed processing system for solvents and hazardous materials
Endorsements
See What People Are Saying About Our Stainless Steel Centrifuges
“The explosion-proof PowerFuge closed up our solvent process for a safe and environmentally friendly manufacturing method.”
Senior Process Engineer, Pigments
“The PowerFuge closed up our ethanol process and its automatic scraping improved our recovery.”
Associate Director of Vaccine Franchise
“Removing large particles with PowerFuge reduced the number of filtration steps.”
Manufacturing Engineer, Pigments
“The high g-force of the PowerFuge [e. Coli lysate clarification] reduced our downstream clarification needs.”
Senior Process Development Scientist, pDNA
"Gentle handling of our cells at scale resulted in higher VLP recovery.”
Director of Operations, Vaccine Manufacturing
Scale up or down with PowerFugeⓇ
Our PowerFuge family enables efficient liquid-solid separation. Its durable stainless steel construction handles bacteria, fungi, proteins, and submicron particles from small to large-scale applications.
Frequently Asked Questions (FAQs)
How does the PowerFuge P12 ensure complete liquid-solid separations?
The PowerFuge P12 is engineered for optimal performance in liquid-solid separations, producing the driest cake for maximum yield. Its advanced design allows it to handle high-density feeds without the need for dilution, ensuring efficient separation, even under challenging conditions.
What automated features does the PowerFuge P12 offer to enhance operational efficiency?
The PowerFuge P12 comes with automated solids removal and is fully capable of CIP (Clean-In-Place) and SIP (Steam-In-Place) processes. This automation not only streamlines operations but also optimizes processes, reducing the need for manual intervention and ensuring consistent, high-quality output.
What design and safety certifications are available for the PowerFuge P12?
The PowerFuge P12 is available with several design options to meet regulatory and safety requirements, including CE Marking, 2 bar Steam-In-Place (ASME/PED Rated), and configurations for hazardous environments. Additionally, the unit features an integrated cooling jacket and spindle cooling unit, along with a service hoist for easy maintenance and repair, contributing to longer component life and enhancing operational safety.
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